| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
|
|---|
| Research Abstract |
In order to understand principle of protein structure and improve protein structure prediction accuracy, we have developed a De Novo protein structure prediction method focusing on physico-chemical properties of local sequence. Especially, a new implicit solvent model called "ghost water model" has been developed for the purpose of evaluating energies of local structures. We performed large scale structure prediction benchmark test and found that local structures of the native are generally stable even if these are excised from a entire structure.
|
