| Project/Area Number |
20770126
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biophysics
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| Research Institution | Shizuoka University |
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Principal Investigator |
OKA Toshihiko Shizuoka University, 理学部, 助教 (60344389)
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| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 膜蛋白質 / 巨大結晶化 / 巨大結晶作成 / 脂質 / 高分解能結晶構造解析 |
|---|
| Research Abstract |
I tried to make a large crystal of a membrane protein, bacteriorhodopsin, which is enough to decide detailed structure including the positions of hydrogen atoms. But I could not make a large crystal during this research period. On the other hand, it has been revealed that structural transition of lipids effects to the crystallization of bacteriorhodopsin, which is an important aspect of crystallization mechanism of membrane proteins in lipids.
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