Analysis of proteins regulating bacterial cell division site
| Project/Area Number |
20770142
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Molecular biology
|
|---|
| Research Institution | University of Toyama |
|---|
Principal Investigator |
OKUNO Takashi University of Toyama, 大学院・医学薬学研究部(薬学), 准教授 (80411031)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | 細胞分裂 / ATPase / 分子間相互作用 |
|---|
| Research Abstract |
We have studied on the Min proteins (MinC,D,E) which regulates position of ceptum ring (FtsZ ring) formation in E.coli. he results of FRET analysis indicated that MinC interacts with FtsZ monomer rather than FtsZ polymer in the solution. It is suggested that interaction between monomeric FtsZ and MinC is important for controlling of FtsZ polymerization by MinC. On the other hand, in vitro analysis of mutant proteins of MinD indicated membrane binding of MinD requires not only ATP binding to nucleotide binding pocket of MinD, but also other factors.
|
Report
(3 results)
Research Products
(13 results)
