Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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Research Abstract |
Apl1 (a PthA homologue) of Xanthomonas axonopodis pv. citri (Xac) is one of the AvrBs3/PthA effectors secreted via type III secretion system and a major virulence factor responsible for canker formation. The enzyme activity of pectin methylesterase (PME) that was isolated as the Apl1-binding protein from citrus was affected by binding with Apl1. The symptoms observed in the silencing area of TERT (telomerase reverse transcriptase), whose translational product is one of the components of telomerase, were more attenuated compared to those observed in the nonsilencing control area. These results suggest that PME and telomerase activity play important roles in infection and virulence of Xac.
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