Screening of peptide inhibiting biofilm formation from glycated protein
| Project/Area Number |
20780098
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Food science
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
NOMA Seiji 九州大学, 大学院農学研究院, 助教 (40392071)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Keywords | 食品 / 衛生 / 蛋白質 / 糖 / 細菌 / バイオフィルム / メイラード反応 |
|---|
| Outline of Final Research Achievements |
Since microorganisms show high resistance to chemical and physical stresses when forming biofilm, inhibition of biofilm formation is important for their effective inactivation. We screened a novel peptide inhibiting biofilm formation of Staphylococcus aureus from α-lactoalbumin glycated by glucose. The peptide without glycation did not show the inhibitory effect. The glycated peptide inhibited the proliferation of S. aureus cells.
|
Report
(3 results)
Research Products
(3 results)
