The roles of fatty acid binding protein inthe pathogenesis of lifestyle related disease

• Project/Area Number: 20780104
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Food science
• Research Institution: Chubu University
• Principal Investigator: KUSUDO Tatsuya Chubu University, 生命健康科学部, 助手 (00460535)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: FABP3 / 脂肪酸結合タンパク質 / インスリン抵抗性

Research Abstract

Fatty acid binding protein 3 is an intracellular translocator of lipids. In this study, we examined the effects of FABP3 on the pathogenesis of lifestyle-related disease and found that FABP3 could affect the insulin signaling and energy metabolism.

Research Products

• [Journal Article] Induction of fatty acid-binding protein 3 in brown adipose tissue correlates with increased demand for adaptive thermogenesis in rodents. (2008)
  • Author(s): Yamashita H, Wang Z, Wang Y, Segawa M, Kusudo T, Kontani Y.
  • Journal Title: Biochem Biophys Res Commun. 377(2) Pages: 632-5
  • Peer Reviewed
• [Journal Article] Induction of fatty acid-binding protein 3 in brown adipose tissue correlates with increased demand for adaptive thermogenesis in rodents (2008)
  • Author(s): Yamashita hitoshi
  • Journal Title: Biochem. Biophys. Res. Commun 377 Pages: 632-635
  • Peer Reviewed
• [Presentation] 骨格筋における脂肪酸結合タンパク質3の発現上昇と生活習慣病のかかわりについて (2009)
  • Author(s): 楠堂達也、山下均
  • Organizer: 第30回日本肥満学会大会
  • Place of Presentation: アクトシティ浜松
• [Presentation] 骨格筋における脂肪酸結合タンパク質3の発現上昇と生活習慣病のかかわりについて (2009)
  • Author(s): 楠堂達也
  • Organizer: 日本肥満学会
  • Place of Presentation: アクトシティ浜松(静岡県)
• [Presentation] 脂肪酸結合タンパク質(EABP3)におけるSNPs由来変異体の機能解析 (2008)
  • Author(s): 楠堂達也
  • Organizer: 日本生化学会
  • Place of Presentation: 神戸ポートアイランド
  • Year and Date: 2008-12-12
• [Presentation] 脂肪酸結合タンパク質(FABP3)の発現誘導と内臓肥満 (2008)
  • Author(s): 山下均
  • Organizer: 日本肥満学会
  • Place of Presentation: 大分全日空ホテル
  • Year and Date: 2008-10-17
• [Presentation] 脂肪酸結合タンパク質(FABP3)におけるSNPs由来変異体の機能解析 (2008)
  • Author(s): 楠堂達也、山下均
  • Organizer: 第81回日本生化学会大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 脂肪酸結合タンパク質(FABP3)の発現誘導と内臓肥満 (2008)
  • Author(s): 山下均、楠堂達也
  • Organizer: 第29回日本肥満学会大会
  • Place of Presentation: 大分全日空ホテル