| Project/Area Number |
20780193
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Zootechnical science/Grassland science
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
SUGINO Toshihisa Hiroshima University, 大学院・生物圏科学研究科, 助教 (90363035)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 子牛 / 早期離乳 / グレリン / GLP-1 / 消化管ホルモン |
|---|
| Research Abstract |
Our objectives were to determine the effects of feeding, circulating glucose and volatile fatty acids (VFA) on blood GLP-1 and ghrelin concentrations in calves around weaning stage. In experiment 1, weaning increased basal blood level of GLP-1, but basal level of ghrelin was decreased. And the changed in blood these hormones were related the blood glucose and VFA levels. In experiment 2, VFA injection induced a greater increase in blood GLP-1 and a greater decrease in blood ghrelin levels around weaning stage. However, glucose injection was not affected these hormones concentrations. In experiment 3, GLP-1 and ghrelin injection were strongly stimulated insulin and GH secretions after weaning compared with that before weaning.
|
