| Project/Area Number |
20780196
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Meiji University |
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Principal Investigator |
ASANUMA Narito Meiji University, 農学部, 講師 (50366902)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 畜産学 / 栄養学 / 細菌学 / 遺伝子 / 応用微生物 / ルーメンバクテリア / ルーメンアシドーシス / Streptococcus bovis / クォーラムセンシング / 増殖制御ペプチド / ComC / 転写調節 |
|---|
| Research Abstract |
It is desirable to consider a new strategy to prevent rumen acidosis, which is cased when ruminants are fed high-concentrate diets, because the dose of antibiotics and ionophores may cause the risk of residual antibiotics in animal products. Therefore, to prevent the overgrowth of the bacterium causing rumen acidosis (Streptococcus bovis), I identified a chemical signaling molecule to control the growth, which may be related to the change in the expression of several proteins, in S. bovis. This result may contribute to the development of a new strategy for the control of S. bovis overgrowth and the prevention of rumen acidosis.
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