| Project/Area Number |
20780218
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied veterinary science
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| Research Institution | Gifu University |
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Principal Investigator |
OHYA Kenji Gifu University, 応用生物科学部, 准教授 (50402219)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 人獣共通感染症 / 偏性細胞内寄生細菌 / クラミジア / 封入体 / 感染特異抗原 / 診断 / 病原性 |
|---|
| Research Abstract |
cell cytoplasm, called "inclusion body". In this study, aiming at understanding the relationship between biogenesis of inclusion bodies of Chlamydophila psittaci, a causative agent for a zoonotic psittacosis, and its pathogenesis. As a result of C. psittaci library screening by using C. psittaci-infection specific serum, the clone encoding one of the polymorphic membrane protein (pmp) genes was obtained (temporary named as PmpX), and functional analysis of PmpX was done. Currently, further investigation of the role of C. psittaci Pmp family proteins (especially PmpX) in biogenesis of chlamydial inclusion bodies and in pathogenesis are on going.
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