Synthesis of Polymer-Supported Chiral Dirhodium (II) Complexes and Asymmetric Reactions Using These Catalysts
| Project/Area Number |
20790002
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | Hokkaido University |
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Principal Investigator |
NAMBU Hisanori Hokkaido University, 大学院・薬学研究院, 助教 (80399956)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 有機化学 / 合成化学 / 不斉触媒反応 / 固相遷移金属 / ロジウム(II)錯体 / ラジカル重合反応 / アミノ化反応 / 1, 3-双極付加環化反応 / 1,3-双極付加環化反応 / カルボニルイリド / ナイトレン / ロジム(II)錯体 / C-H挿入反応 / カルベン |
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| Research Abstract |
Synthesis of polymer-supported Rh_2(S-TFPTTL)_4 and Rh_2(S-TCPTTL)_4, the fluorinated or chlorinated analogues of Rh_2(S-PTTL)_4, has been achieved. Asymmetric amination of silyl enol ether and asymmetric 1,3-dipolar cycloaddition of carbonyl ylide using these polymer-supported Rh (II) complexes afforded similar product yields and enantioselectivities as those found with homogeneous Rh_2(S-TFPTTL)_4 and Rh_2(S-TCPTTL)_4.
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Report
(3 results)
Research Products
(21 results)
