| Project/Area Number |
20790004
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | Tohoku University |
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Principal Investigator |
KIYOFUMI Inamoto Tohoku University, 大学院・薬学研究科, 助教 (30359533)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | パラジウム / 炭素-水素結合官能基化 / 炭素-窒素結合形成反応 / 炭素-硫黄結合形成反応 / 複素環化合物 / 2-キノリノン / ベンゾチアゾール / 再酸化剤 / 炭素-水素結合活性化 / インドール / ベンゾチオフェン |
|---|
| Research Abstract |
Catalytic methods for the synthesis of heterocyclic compounds, such as indazoles, indoles, 2-quinolinones, benzo[b]thiophenes, and benzothiazoles, were developed utilizing palladium-catalyzed C-H functionalization followed by intramolecular C-N or C-S bond formation. These heterocyclic compounds are subunits of a range of biologically active pharmaceuticals and natural products.
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