Functional and molecular analysis of DSCR1 as a regulator of vascular morphology
| Project/Area Number |
20790168
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Nippon Medical School |
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Principal Investigator |
FUJIWARA Masakazu Nippon Medical School, 老人病研究所, 助教 (20312069)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 発生学 / 形態形成学 / 血管新生 / 血管形成 / 血管内皮細胞 |
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| Research Abstract |
Morphology of blood vessels is diverse. However, we do not know how these morphological variations are made during vasculogenesis/angiogenesis. In this study, we found that DSCR1 regulates the morphology of blood vessels by suppressing the branching of blood vessels during vasculogenesis/angiogenesis. In the near future, we may generate blood vessels with appropriate morphology for the patients by using DSCR1 as a new vasculogenesis/angiogenesis suppressor.
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Report
(3 results)
Research Products
(9 results)
