Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Research Abstract |
In the present study, we have established the methods to prepare white adipocytes suitable for various physiological experiments. In this preparation, it was clarified that the volume-sensitive chloride channel is expressed and involved in volume regulation in white adipocytes. Expression level of this channel was decreased in white adipocytes from diabetic animals. Moreover, it was also revealed that white adipocytes express MIC channel which is regulated by both intracellular and extracellular magnesium ions.
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