Novel mechanisms of t-PA-dependent liver regeneration
Project/Area Number |
20790182
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
General physiology
|
Research Institution | Kinki University |
Principal Investigator |
KAWAO Naoyuki Kinki University, 医学部, 助教 (70388510)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | t-PA / 細胞内シグナル伝達 / 肝再生 / 細胞内シグナル / プラスミノゲン / シグナル伝達 |
Research Abstract |
The roles of plasminogen activator (PA) /plasmin system in liver repair was examined. Then, the PA/plasmin system contributes to hepatocyte proliferation. In addition, plasminogen is essential for triggering a cascade of sequential repair responses after liver injury.
|
Report
(3 results)
Research Products
(10 results)