| Project/Area Number |
20790235
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|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General medical chemistry
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| Research Institution | Saitama Medical University |
|---|
Principal Investigator |
MITSUI Kaoru Saitama Medical University, 大学院・医歯学総合研究科, 講師 (40324975)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Keywords | iPS細胞 / ウイルスベクター / ips細胞 |
|---|
| Research Abstract |
In order to generate safety induced pluripotent stem cells (iPS cells), two chromosome non-integration viral vectors infected to murine embryonic fibroblasts or human fibroblasts. However, I did not demonstrated successful reprogramming of any fibroblasts under culture conditions necessary for induction of iPS cells. In addition, I attempted to generate adenoviral vectors, which specifically expressed in undifferentiated state.
|
