Research Project
Grant-in-Aid for Young Scientists (B)
Large-scale mathematical model of metabolism in human red blood cells predicted that high extracellular adenosine resulted in decrease in intracellular ATP levels, and that the reduction of cellular energy would be compensated by glycolytic activation through hypoxia-induced hemoglobin-transition. A simulation model that can reproduce the metabolic behavior in long and cold stored red blood cells in MAP solution was also developed. The MAP-stored model would contribute to high-throughput and low-cost screening of optimized stored condition.
All 2010 2009 2008 Other
All Journal Article (10 results) (of which Peer Reviewed: 8 results) Presentation (18 results) Book (1 results) Remarks (2 results)
J Biomed Biotechnol (in press)
Redox Signal (in press)
J. Clin. Biochem. Nutr. 46(2)
Pages: 126-134
Advances in Experimental Medicine and Biology 662
Pages: 109-114
J Clin Biochem Nutr. 46(2)
Adv Exp Med Biol. 66
J Biotechnol 144(3)
Pages: 212-223
人工血液 17(1)
Pages: 37-43
J Biotechnol 114(3)
人工血液 17(1)(掲載決定済、未刊行)
