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Development of a novel diagnostic method for fine needle aspiration cytology of thyroid using liquid based cytology

Research Project

Project/Area Number 20790280
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Human pathology
Research InstitutionNagoya University

Principal Investigator

HASHIMOTO Katsunori  Nagoya University, 医学部・保健学科, 助教 (70324423)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords病理学 / 細胞診 / 甲状腺 / 液状処理細胞診
Research Abstract

The conventional method of diagnostic cytology is the laboratory procedure to depend on knowledge and experience of cytopathologist and cytotechnologist, hence the problem such as inter-observer variability and false diagnosis may occur. To establish objective diagnostic method that was not based on the subjectivity of the investigator, this study assessed novel method that applied morphometric analysis and immunocytochemistry to LBC specimen of thyroid. This method was able to discriminate malignancy group (papillary carcinoma and follicular carcinoma) and benign group (follicular adenoma, adenomatous goiter and Basedow's disease) with high probability.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (12 results)

All 2009 2008

All Presentation (11 results) Book (1 results)

  • [Presentation] 甲状腺乳頭癌の形態計測的解析(液状処理細胞診と従来法との比較)2009

    • Author(s)
      橋本克訓, 他
    • Organizer
      第48回日本臨床細胞学会秋期大会
    • Place of Presentation
      JALシーホークホテル福岡(福岡市)
    • Year and Date
      2009-10-31
    • Related Report
      2009 Final Research Report
  • [Presentation] 液状処理細胞診検体を用いた腹水腺癌細胞と中皮細胞の免疫組織学的検討2009

    • Author(s)
      森本亜由美、橋本克訓, 他
    • Place of Presentation
      JALシーホークホテル福岡(福岡市)
    • Year and Date
      2009-10-31
    • Related Report
      2009 Final Research Report
  • [Presentation] 甲状腺乳頭癌の形態計測的解析(液状処理細胞診と従来法との比較)2009

    • Author(s)
      橋本克訓
    • Organizer
      第48回日本臨床細胞学会秋期大会
    • Place of Presentation
      JALシーホークホテル福岡(福岡県)
    • Year and Date
      2009-10-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] 液状処理細胞診検体を用いた腹水腺癌細胞と中皮細胞の免疫組織学的検討2009

    • Author(s)
      森本亜由美
    • Organizer
      第48回日本臨床細胞学会秋期大会
    • Place of Presentation
      JALシーホークホテル福岡(福岡県)
    • Year and Date
      2009-10-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] 液状処理細胞診における甲状腺病変の細胞像の形態計測的解析2009

    • Author(s)
      橋本克訓, 他
    • Organizer
      第5 6回日本臨床検査医学会学術集会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2009-08-28
    • Related Report
      2009 Final Research Report
  • [Presentation] 液状処理細胞診における甲状腺病変の細胞像の形態計測的解析2009

    • Author(s)
      橋本克訓
    • Organizer
      第56回日本臨床検査医学会学術集会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2009-08-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Morphometric and FISH analysis of mesothelial cells and adenocarcinoma using LBC2008

    • Author(s)
      Ayumi Morimoto
    • Organizer
      第47回日本臨床細胞学会秋期大会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] 液状処理細胞診を用いた甲状腺病変の免疫細胞化学的、形態計測的鑑別診断の基礎的研究2008

    • Author(s)
      橋本克訓, 他
    • Organizer
      第47回日本臨床細胞学会秋期大会
    • Place of Presentation
      グランドプリンスホテル高輪(東京都港区)
    • Year and Date
      2008-11-14
    • Related Report
      2009 Final Research Report
  • [Presentation] Morphometric and FISH analysis of mesothelial cells and adenocarcinoma using LBC.2008

    • Author(s)
      Ayumi Morimoto, Katsunori Hashimoto, Toyoharu Yokoi, et al.
    • Organizer
      The 15th Japan-Thai International Cytology Workshop.
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-11-14
    • Related Report
      2009 Final Research Report
  • [Presentation] 液状処理細胞診を用いた甲状腺病変の免疫細胞化学的、形態計測的鑑別診断の基礎的研究2008

    • Author(s)
      橋本克訓
    • Organizer
      第47回日本臨床細胞学会秋期大会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] 細胞検査士養成のアンケート調査2008

    • Author(s)
      岩田英紘
    • Organizer
      第3回日本臨床検査教育学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2008-08-21
    • Related Report
      2008 Annual Research Report
  • [Book] 新版細胞診断学入門2009

    • Author(s)
      杜本幹博
    • Publisher
      名古屋大学出版会
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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