Global analysis for miRNA of cancer stemcells in follicular lymphoma
| Project/Area Number |
20790288
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Human pathology
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| Research Institution | Iwate Medical University |
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Principal Investigator |
ABO Akiko 岩手医科大学, 医学部, 講師 (80326686)
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| Project Period (FY) |
2008 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥5,030,906 (Direct Cost: ¥3,869,928、Indirect Cost: ¥1,160,978)
Fiscal Year 2011: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,000,906 (Direct Cost: ¥769,928、Indirect Cost: ¥230,978)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 濾胞性リンパ腫 / がん幹細胞 / microRNA / SP細胞 / miRNA |
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| Research Abstract |
We investigated the differential expression of miRNAs between SP cells and non-SP cells of human follicular lymphomas(FLs). This study demonstrates that down expression of microRNA contribute to the down regulation of multipotent stem cell transcription factor in SP cells, and that over expression of microRNA targeting BCL6.
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Report
(5 results)
Research Products
(26 results)
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[Journal Article]2008
Author(s)
Mitomo S, Maesawa C, Ogasawara S, Iwaya T, Shibazaki M, YashimaAbo A, Kotani K, Oikawa H, Sakurai E, Izutsu N, Kato K, Komatsu H, Ikeda K, Wakabayashi G, Masuda T
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Journal Title
Cancer Sci
Volume: 99
Pages: 280-6
Related Report
Peer Reviewed
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[Presentation] 腎腫瘍の一例2012
Author(s)
阿保亜紀子
Organizer
日本病理学会東北支部学術集会
Place of Presentation
艮陵会館
Year and Date
2012-02-12
Related Report
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