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Microsatellite instability and DNA promoter methylation of reactive stroma in prostatic carcinoma

Research Project

Project/Area Number 20790289
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Human pathology
Research InstitutionKitasato University

Principal Investigator

YANAGISAWA Nobuyuki  Kitasato University, 医学部, 講師 (80337914)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords病理学 / 前立腺癌 / MSI / メチル化 / 癌反応性間質 / 分子病理学
Research Abstract

Reactive stromal grades (RSGs) of 226 prostatic carcinomas were different between their localization in the prostatic gland. Compared with the low grade cancers (such as TZ cancers), more aggressive cancers (PZ cancers) showed high RSGs with significance.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (1 results)

All 2008

All Journal Article (1 results) (of which Peer Reviewed: 1 results)

  • [Journal Article] Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy2008

    • Author(s)
      Yanagisawa N., Li R., Rowley D., Hao L., Kadman D., Miles B.J., Wheeler T.M., Ayala G.E.
    • Journal Title

      Hum Pathol 39(2)

      Pages: 282-291

    • Related Report
      2009 Final Research Report
    • Peer Reviewed

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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