Rapid detection of alteration of outer membrane proteins conferring antimicrobial resistance in Pseudomonas aeruginosa and application to surveillance
| Project/Area Number |
20790413
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Laboratory medicine
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| Research Institution | Tottori University |
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Principal Investigator |
HORII Toshinobu Tottori University, 医学部, 准教授 (80283430)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 臨床微生物学 / 緑膿菌 / カルバペネム系薬 / 外膜タンパク質 / 抗菌薬耐性 / OprD / OprM |
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| Research Abstract |
Rapid detection of OprD alteration conferring carbapenem resistance in Pseudomonas aeruginosa was developed. To survey carbapenem resistance caused by OprD alteration, carbapenem-resistant P. aeruginosa isolates were collected from all over the country and detected the alteration using our newly developed methods.
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Report
(4 results)
Research Products
(23 results)
