The study of in utero exposure of n-EtFOSE, persistent fluorinated chemical

• Project/Area Number: 20790420
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Hygiene
• Research Institution: Suzuka University of Medical Science
• Principal Investigator: BAN Susumu Suzuka University of Medical Science, 薬学部, 助手 (30399828)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
• Keywords: 次世代影響 / 内分泌撹乱物質 / 環境 / 衛生

Research Abstract

The influences of exposure to PFOS (perfluorooctane sulfonate) are reported by epidemiological studies and animal studies. Though n-EtFOSE (n-ethylperfluorooctane sulfonate amide ethanol) is one of the materials for PFOS synthesis, it is not well known about its influences. We conducted the in utero n-EtFOSE exposure study. We showed that in utero exposure to N-EtFOSE causes the effects to the development and functions of placenta resulted in the fetal growth delay.