Epidemiological study between HPV infection and risk of head and neck cancer

• Project/Area Number: 20790435
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Hygiene
• Research Institution: Aichi Cancer Center Research Institute
• Principal Investigator: SUZUKI Takeshi Aichi Cancer Center Research Institute, 大学院・医学研究科, 助教 (70416163)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 予防医学 / 頭頸部がん / HPV / リスク / 喫煙 / 飲酒 / 交互作用

Research Abstract

This study aims to clarify the association between HPV infection and head and neck cancer risk and obtains the evidence for the prevention.

Research Products

• [Journal Article] Impact of smoking on lung cancer risk is stronger in those with the homozygous aldehyde dehydrogenase 2 (ALDH2) null allele in a Japanese population. (2010)
  • Author(s): Park JY, Matsuo K, Suzuki T, Ito H, Hosono S, Kawase T, Watanabe M, Oze I, Hida T, Yatabe Y, Mitsudomi T, Takezaki T, Tajima K, Tanaka H.
  • Journal Title: Carcinogenesis 31 Pages: 660-5
  • Peer Reviewed
• [Journal Article] Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population. (2009)
  • Author(s): Oze I, Matsuo K, Suzuki T, Kawase T, Watanabe M, Hiraki A, Ito H, Hosono S, Ozawa T, Hatooka S, Yatabe Y, Hasegawa Y, Shinoda M, Kiura K, Tajima K, Tanimoto M, Tanaka H.
  • Journal Title: Cancer Epidemiol Biomarkers Prev 18 Pages: 3097-102
  • Peer Reviewed
• [Journal Article] Impact of alcohol consumption with polymorphisms in alcohol-metabolizing enzymes on pancreatic cancer risk in Japanese. (2009)
  • Author(s): Kanda J, Matsuo K, Suzuki T, Kawase T, Hiraki A, Watanabe M, Mizuno N, Sawaki A, Yamao K, Tajima K, Tanaka H.
  • Journal Title: Cancer Sci 100 Pages: 296-302
  • NAID: 10025142499
  • Peer Reviewed
• [Journal Article] Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population. (2009)
  • Author(s): Oze I, Matsuo K, Suzuki T, 他
  • Journal Title: Cancer Epidemiol Biomarkers Prev 18 Pages: 3097-3102
  • Peer Reviewed
• [Journal Article] One-carbon metabolism-related gene polymorphisms and risk of breast cancer. (2008)
  • Author(s): Suzuki T, Matsuo K, Hirose K, Hiraki A, Kawase T, Watanabe M, Yamashita T, Iwata H, Tajima K.
  • Journal Title: Carcinogenesis 29 Pages: 356-62
  • Peer Reviewed
• [Journal Article] Anthropometric factors at age 20 years and risk of thyroid cancer. (2008)
  • Author(s): Suzuki T, Matsuo K, Hasegawa Y, Hiraki A, Kawase T, Tanaka H, Tajima K.
  • Journal Title: Cancer Causes Control 19 Pages: 1233-42
  • Peer Reviewed
• [Journal Article] Effect of soybean on breast cancer according to receptor status: a case-control study in Japan. (2008)
  • Author(s): Suzuki T, Matsuo K, Tsunoda N, Hirose K, Hiraki A, Kawase T, Yamashita T, Iwata H, Tanaka H, Tajima K.
  • Journal Title: Int J Cancer 123 Pages: 1674-80
  • Peer Reviewed
• [Journal Article] Alcohol drinking and one-carbon metabolism-related gene polymorphisms on pancreatic cancer risk. (2008)
  • Author(s): Suzuki T, Matsuo K, Sawaki A, Mizuno N, Hiraki A, Kawase T, Watanabe M, Nakamura T, Yamao K, Tajima K, Tanaka H.
  • Journal Title: Cancer Epidemiol Biomarkers Prev 17 Pages: 2742-7
  • Peer Reviewed
• [Journal Article] One-carbon metabolism-related gene polymorphisms and risk of breast cancer. (2008)
  • Author(s): Suzuki T.
  • Journal Title: Carcinogenesis 29 Pages: 356-362
  • Peer Reviewed
• [Journal Article] Anthropometric factors at age 20 years and risk of thyroid cancer. (2008)
  • Author(s): Suzuki T.
  • Journal Title: Cancer Causes Control 19 Pages: 1233-1242
  • Peer Reviewed
• [Journal Article] Effect of soybeen on breast cancer according to receptor status: a case-control study in Japan. (2008)
  • Author(s): Suzuki T.
  • Journal Title: Int J Cancer 123 Pages: 1674-1680
  • Peer Reviewed
• [Journal Article] Alcohol drinking and one-carbon metabolism-related gene polymorphisms on pancreatic cancer risk. (2008)
  • Author(s): Suzuki T.
  • Journal Title: Cancer Epidemiol Biomarkers Prev. 17 Pages: 2742-2747
  • Peer Reviewed
• [Journal Article] Comparison between Self-reported Facial Flushing After Alcohol Consumption and ALDH2 Glu504Lys Polymorphism for the Risk of Upper Aerodigestive Tract Cancer in a Japanese Population.
  • Author(s): Oze I, Matsuo K, Hosono S, Ito H, Kawase T, Watanabe M, Suzuki T, Hatooka S, Yatabe Y, Hasegawa Y, Shinoda M, Tajima K, Tanaka H.
  • Journal Title: Cancer Science
  • NAID: 10027830779
  • Peer Reviewed
• [Presentation] 日本人におけるアルコール脱水素酵素遺伝子多型の上部気道・消化管がんに与える影響 (2009)
  • Author(s): 尾瀬功, 松尾恵太郎, 鈴木勇史, 川瀬孝和, 伊藤秀美, 細野覚代, 渡邉美貴, 波戸岡俊三, 長谷川泰久, 篠田雅幸, 田島和雄, 田中英夫
  • Organizer: 日本癌学会総会
  • Place of Presentation: 横浜
• [Presentation] 上部気道・消化器がんと歯磨き回数の関係 (2009)
  • Author(s): 佐藤文仁, 尾瀬功, 松尾恵太郎, 鈴木勇史, 山本憲幸, 川瀬孝和, 渡邉美貴, 波戸岡俊三, 長谷川泰久, 篠田雅幸, 上田実, 田島和雄, 田中英夫
  • Organizer: 日本癌学会総会
  • Place of Presentation: 横浜
• [Presentation] アルコール脱水素酵素遺伝子ADH4, ADH7の遺伝子多型と上気道・消化管がんの危険性 (2009)
  • Author(s): 尾瀬功、松尾恵太郎、鈴木勇史、川瀬孝和、田中英夫、田島和雄
  • Organizer: がん予防大会
  • Place of Presentation: 名古屋
• [Presentation] 日本人における頭頸部・食道がんに対するブラッシング習慣のがん予防効果の検討 (2009)
  • Author(s): 佐藤文仁、松尾恵太郎、鈴木勇史、川瀬孝和、渡邊美貴、田島和雄、田中英夫
  • Organizer: がん予防大会
  • Place of Presentation: 名古屋
• [Presentation] 体格と甲状腺がんのリスク (2008)
  • Author(s): 鈴木勇史
  • Organizer: 日本癌学会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-10-29