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A novel diagnosis of acute cardiac death using Tenascin C (TN-C)

Research Project

Project/Area Number 20790462
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Legal medicine
Research InstitutionKumamoto University

Principal Investigator

OHTSU Yuki  Kumamoto University, 大学院・生命科学研究部, 技術専門職員 (90404342)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
KeywordsテネイシンC(TN-C) / 急性心臓死 / 細胞傷害マーカー / 法医診断学 / テネイシンC (TN-C) / 法医病理学
Research Abstract

Tenascin C (TN-C) was applied to postmortem serum samples and their levels were evaluated in 101 forensic autopsy cases within 48 postmortem hours. TN-C levels were 24.0-1,000< ng/ml in 101 forensic autopsy cases, most of which were quite higher than those of clinical levels. There were no relationship between the TN-C levels and autopsy data, such as cause of death, postmortem interval, agonal period time and serum CRP levels. Histopathology of cardiac tissues regarding their inflammation stages are now progressing.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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