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The effect of prevention to the psychosomatic stress : The proposal of the stress care dock

Research Project

Project/Area Number 20790473
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field General internal medicine (including Psychosomatic medicine)
Research InstitutionKagoshima University

Principal Investigator

NAKAHARA Toshihiro  Kagoshima University, 医歯学総合研究科, 研究員 (50433082)

Research Collaborator 原田 敏郎  鹿児島大学, 大学病院・医歯学 総合研究科社会行動医学講座・心身内科学講座
安原 大輔  鹿児島大学, 大学病院・医歯学 総合研究科社会行動医学講座・心身内科学講座
浅川 明弘  鹿児島大学, 大学病院・医歯学 総合研究科社会行動医学講座・心身内科学講座
乾 明夫  鹿児島大学, 大学病院・医歯学 総合研究科社会行動医学講座・心身内科学講座
中原 和彦  ヘルスアートクリニックくまもと
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsストレス / 栄養学 / 臨床 / 予防医学 / 補完・代替医療
Research Abstract

We recruited a variety of people who were evaluated the appetite stimulated peptides related to the stress, and the materials related to the oxidative stress. As a result of peptides related to the appetite, there were a few significant changes between the thin group and the obesity group. However there were no significant changes of autonomics between the obesity and the control. As for oxidative stress, d-ROMs of the cancer group and the obesity group were significantly higher than those of the controls. But the anti-oxidative BAP changed significantly lower in the cancer group, and significantlyhigher in obesity group than those of control.
These results suggested that the feedback system of the simple and quick tests related to the stress may contribute to prevent some diseases.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (14 results)

All 2011 2010 2009 2008

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (4 results) Book (1 results)

  • [Journal Article] Plasma nesfatin-1 concentrations in restricting-type anorexia nervosa.2011

    • Author(s)
      Ogiso K, Asakawa A, Amitani H, Nakahara T, Ushikai M, Haruta I, Koyama KI, Amitani M, Harada T, Yasuhara D, Inui A.
    • Journal Title

      Peptides. 32(1)(Epub 2010 Oct 19)

      Pages: 150-153

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Plasma nesfatin-1 concentrations in restricting-type anorexianervosa.2011

    • Author(s)
      Ogiso K, Asakawa A, Amitani H, Nakahara T, et al
    • Journal Title

      Peptides.

      Volume: Jan 32(1) Pages: 150-153

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in Acyl Ghrelin, Des-acyl Ghrelin, and Ratio of Acyl Ghrelin to Total Ghrelin with Short-term Refeeding in Female Inpatients with Restricting-type Anorexia Nervosa.2010

    • Author(s)
      Koyama KI, Yasuhara D, Nakahara T, Harada T, Uehara M, Ushikai M, Asakawa A, Inui A.
    • Journal Title

      Horm Metab Res. 21;42

      Pages: 595-598

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Plasma obestatin concentrations are negatively correlated with body mass index, insulin resistance index, and plasma leptin concentrations in obesity and anorexia nervosa.2010

    • Author(s)
      Nakahara T, Harada T, Yasuhara D, Shimada N, Amitani H, Sakoguchi T, Kamiji MM, Asakawa A, Inui A.
    • Journal Title

      Biol Psychiatry. 1;64(3)

      Pages: 252-255

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in Acyl Ghrelin, Des-acyl Ghrelin, and Ratio of Acyl Ghrelin to Total Ghrelin with Short-term Refeeding in Female Inpatients with Restricting-type Anorexia Nervosa.2010

    • Author(s)
      Koyama KI, Yasuhara D, Nakahara T, et al.
    • Journal Title

      Horm Metab Res.

      Volume: Apr 21(42) Pages: 595-598

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 中枢性摂食異常症患者と摂食関連ペプチドghrelin, PYY, obestatinについて2009

    • Author(s)
      中原敏博, ら
    • Journal Title

      消化器心身医学 16(1)

      Pages: 103-107

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Japanese Genetic Research Group for Eating Disorders.Psychological and weight-related characteristics of patients with anorexia nervosa-restricting type who later develop bulimia nervosa.2008

    • Author(s)
      Nishimura H, Komaki G, Ando T, Nakahara T, Oka T, Kawai K, Nagata T, Nishizono A, Okamoto Y, Okabe K, Koide M, Yamaguchi C, Saito S, Ohkuma K, Nagata K, Naruo T, Takii M, Kiriike N, Ishikawa T
    • Journal Title

      Biopsychosoc Med. 12;2

      Pages: 5-5

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Plasma obestatin concentrations are negatively correlated with body mass index, insulin resistance index, and plasma leptin concentrations in obesity and anorexia nervosa2008

    • Author(s)
      Nakahara T, et.al.
    • Journal Title

      Biological Psychiatry Aug1 ; 64(3)

      Pages: 252-255

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Obestatin, acyl ghrelin, and des acyl ghrelin responces to an oral glucose tolerance test in the resting type of anorexia nervosa2008

    • Author(s)
      Harada T, Nakahara T, et.al.
    • Journal Title

      Biological Psychiatry Jan15 ; 63(2)

      Pages: 245-247

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 癌を含む各種疾患に対する糖鎖フコイダンの効果の検証:酸化ストレスと抗酸化力の変化を検証2009

    • Author(s)
      中原敏博 中原和彦
    • Organizer
      第9回日本抗加齢学会総会
    • Place of Presentation
      東京 一般演題
    • Year and Date
      2009-05-29
    • Related Report
      2010 Final Research Report
  • [Presentation] 癌を含む各種疾患に対する糖鎖フコイダンの効果検証:酸化ストレスなど2009

    • Author(s)
      中原敏博, ら
    • Organizer
      第9回日本抗加齢学会
    • Place of Presentation
      東京
    • Related Report
      2009 Annual Research Report
  • [Presentation] 中枢性摂食異常患者と摂食関連ペプチド:ghrelin、PYY、obestatin について2008

    • Author(s)
      中原敏博、原田敏郎、兒島真哉、安原大輔、島田展裕、濱田聡史、長井信篤、中里雅光、成尾鉄朗、木場正典、田中英世、浅川明弘、乾明夫
    • Organizer
      第70回消化器心身医学研究会
    • Place of Presentation
      福岡 一般演題
    • Year and Date
      2008-05-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 中枢性摂食異常患者と摂食調整ペプチド : ghrelin, PYY, オベスタチンについて2008

    • Author(s)
      中原敏博, 他
    • Organizer
      第70回消化器心身医学研究会
    • Place of Presentation
      福岡県博多市
    • Year and Date
      2008-05-10
    • Related Report
      2008 Annual Research Report
  • [Book] 心療内科実践ハンドブック:症例に学ぶ用語集:ストレス2009

    • Author(s)
      中原敏博、乾明夫
    • Publisher
      マイライフ社
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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