| Project/Area Number |
20790478
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | Nigata University of Phermacy and Applied Life Sciences |
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Principal Investigator |
MICHIKO Sekiya Nigata University of Phermacy and Applied Life Sciences, 薬学部, 助教 (40367412)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 東洋医学 / 筋萎縮性側索硬化症 / 漢方方剤 / 温脾湯 / 生薬 / 藤縮性側索硬化症 / HO-1 / iNOS |
|---|
| Research Abstract |
We investigated the effect of a Chinese prescription, Wen-Pi-Tang, on the ALS model mouse SOD1G93A. Although the oral administration of Wen-Pi-Tang extract to SOD1G93A mice had no significant effect on body weight loss and survival time, Wen-Pi-Tang delayed disease onset. The administration of Wen-Pi-Tang was thought to delay disease onset by inhibiting glial cell activation.
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