Investigation into modifying factors in patients with hypertrophic cardiomyopathy caused by an identical disease-causing mutation
Project/Area Number |
20790533
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Circulatory organs internal medicine
|
Research Institution | Kochi University |
Principal Investigator |
KUBO Toru Kochi University, 教育研究部医療学系, 助教 (80325422)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
|
Keywords | 臨床心血管病態学 / 肥大型心筋症 / 遺伝子 / 臨床 |
Research Abstract |
I investigated the genotype-phenotype correlations in hypertrophic cardiomyopathy (HCM). In genetic analysis, I reported some mutations associated with HCM, particularly mutations in cardiac myosin-binding protein C gene. In the studies of clinical phenotype in HCM, I focused on the left ventricular remodeling of this disease and reported several results including the usefulness of biomarkers for predicting the prognosis.
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Report
(4 results)
Research Products
(62 results)