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Elucidation of the vascular lesion in the high homocysteine model who used CSE knockout mouse

Research Project

Project/Area Number 20790551
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Circulatory organs internal medicine
Research InstitutionKeio University

Principal Investigator

YAMAMOTO Michiko  Keio University, 医学部, 助教 (60445450)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords分子血管病態学 / 血管内皮障害
Research Abstract

This study to make a high homocysteine blood symptom model with CSE knockout mouse is extremely novelty and originality. In addition, we think that it is a study of the utility to approach for vascular lesion onset mechanism of the high homocysteine blood symptom to compare a high homocysteine blood symptom model of the CSE^<-/-> mouse with a CBS^<+/-> mouse functionally.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (1 results)

All 2008

All Presentation (1 results)

  • [Presentation] N-アセチルシステインおよびNaHSの血管拡張作用とその機序-ATP依存性カリウムチャンネルの関与2008

    • Author(s)
      山本美智子
    • Organizer
      Molecular Cardiovascular Conference
    • Place of Presentation
      北海道小樽
    • Related Report
      2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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