Research Project
Grant-in-Aid for Young Scientists (B)
We previously proposed a strategy for selective suppression of mutant allele. We succeeded in mutant gene suppression in the target organ of mice, using in vivo administered adeno-associated viral vectors. Our method may prove useful for siRNA-based gene therapy for inherited diseases.
All 2009 2008 Other
All Journal Article (5 results) (of which Peer Reviewed: 2 results) Presentation (5 results) Remarks (3 results)
FEBS Letters 583
Pages: 213-218
Antisense 12
Pages: 37-47
Clinical Neuroscience
Pages: 337-339
Clinical Neuroscience 26
http://www.tmd.ac.jp/med/nuro/study.html#b