Pathological study and transplantation of Bone marrow stromal cell in a model of amyotrophic lateral sclerosis
| Project/Area Number |
20790614
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurology
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| Research Institution | Tottori University |
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Principal Investigator |
KITAYAMA Michio Tottori University, 医学部, 助教 (70379650)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | モデルマウス / 筋萎縮性側索硬化症 / 骨髄間質細胞移植 |
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| Research Abstract |
Histological examination of the transgenic mice tissue at ventral horn using General stain and immunohistochemisity. Although the result is a nerve cell shedding onset after severe would mutant SOD1 are each in nerve cells, aging degenerative in organelle and inclusion bodies in cells had emerged from early. Therapeutic effect of Bone marrow stromal cell transplantation for anterior mice in quality between cell bone marrow, after consideration of clinical and pathological tissue chemically. However, as a result, port group in the life-prolonging effects, and histologically also remained a spinal cord ventral horn cells, but as a clinical effect was not enough.
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Report
(4 results)
Research Products
(20 results)
