The role of endothelial progenitor cells and VEGF,VEGF-C in proliferating infantile hemangioma.

• Project/Area Number: 20790743
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Pediatrics
• Research Institution: Jichi Medical University
• Principal Investigator: NAKAMURA Sachie Jichi Medical University, 医学部, 助教 (20382955)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 癌 / 細胞・組織

Research Abstract

hemangioma and neuroblastoma in children were characterized by increased expression of VEGF-A. The expression of VEGF-A is higher in proliferating hemangioma than hemangioma in stable state. In neuroblastoma patients, the expression of VEGF-A remained high-revel after tumorectomy. VEGF-C and VEGF-D are significantly lower in infantile hemangioma.

Research Products

• [Presentation] (2011)
  • Organizer: 第53回日本小児血液・がん学会学術集会
  • Place of Presentation: 群馬(発表予定)
• [Presentation] 日齢1に進行性の皮膚壊疽で発症した血球貪食性リンパ組織球症(HLH)の一例 (2009)
  • Author(s): 中村幸恵、池田尚広、柏井良文、森雅人、矢田ゆかり、郡司勇治、高橋尚人、森本哲、桃井真里子
  • Organizer: 第51回日本小児血液学会
  • Place of Presentation: 東京ベイホテル東急
  • Year and Date: 2009-11-29
• [Presentation] 日齢1から制御不能な高サイトカイン血症と進行性の皮膚壊疽をきたした乳児例 (2009)
  • Author(s): 中村幸恵、池田尚広、森雅人、柏井良文、郡司勇治、高橋尚人、森本哲、桃井真里子
  • Organizer: 第19回日本小児リウマチ学会
  • Place of Presentation: 京都リサーチパーク
  • Year and Date: 2009-10-04
• [Presentation] AML(M5)治療終了後1年後に非結核性抗酸菌感染症に罹患した一例 (2008)
  • Author(s): 中村幸恵、早川貴裕、柏井良文、郡司勇治、森本哲、桃井真里子
  • Organizer: 第50回日本小児血液学会
  • Place of Presentation: 幕張メッセ国際会議場
  • Year and Date: 2008-11-14
• [Remarks] ホームページ等