Diagnostic usefulness of salivary steroid hormone measurement by LC-MS/MS in girls with PCOS

Research Project

Project/Area Number	20790745
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Pediatrics
Research Institution	Keio University
Principal Investigator	AMANO Naoko Keio University, 医学部, 助教 (70348689)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000) Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords	小児内分泌学 / 肥満 / 思春期 / ステロイドホルモン / PCOS / ステロイド分析
Research Abstract	I measured salivary free steroid hormones by liquid chromatography-tandem mass spectrometry (LC-MS/MS), and compared the steroid hormone levels of obesity girls to non-obesity girls. The levels of DHEA, androstenedione and testosterone in obesity girls were significantly higher than those in non-obesity girls. I think that the secretions of those androgens are increased in obesity girls as well as adult women with polycystic ovary syndrome.

Report

(3 results)