Analysis of rotavirus antigenemia in hepatopoietic stem cell transplanted children
| Project/Area Number |
20790752
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Fujita Health University |
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Principal Investigator |
SUGATA Ken Fujita Health University, 医学部, 助教 (60454401)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | ロタウイルス / 抗原血症 / 免疫抑制状態 / 造血幹細胞移植 / 抗RV IgG抗体 / HSCT |
|---|
| Research Abstract |
We've already reported that rotavirus antigenemia has been found in immunocompetent rotavirus gastroenteritis patients. However, the pathogenesis of rotavirus infection in immunocompromised transplant recipients remains unclear. Serially collected serum samples obtained from the patients receiving allogeneic hematopoietic stem cell transplants were measured rotavirus antigen levels using a previously established enzyme-linked immunosorbent assay.
Rotavirus antigenemia occurred in hematopoietic stem cell transplant (HSCT) recipients. Although the duration of antigenemia was clearly longer than in immunocompetent rotavirus gastroenteritis patients, the levels of antigen were not as high.
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Report
(4 results)
Research Products
(28 results)
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[Journal Article] Analysis of rotavirus antigenemia and extraintestinal manifestations in children with rotavirus gastroenteritis.2008
Author(s)
Sugata K, Taniguchi K, Yui A, Miyake F, Suga S, Asano Y, Ohashi M, Suzuki K, Nishimura N, Ozaki T, Yoshikawa T.
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Journal Title
Pediatr. 22(2)
Pages: 392-397
Related Report
Peer Reviewed
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[Journal Article] Elevated serum cytokine levels are associated with human herpesvirus 6 reactivation in hematopoietic stem cell transplantation recipients.2008
Author(s)
Fujita A, Ihira M, Suzuki R, Enomoto Y, Sugiyama H, Sugata K, Suga S, Asano Y, Yagasaki H, Kojima S, Matsumoto K, Kato K, Yoshikawa T.
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Journal Title
J.Infect. 57(3)
Pages: 241-248
Related Report
Peer Reviewed
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