Analysis of PDA pathogenesis with novel PDA model mice.
Project/Area Number |
20790775
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Embryonic/Neonatal medicine
|
Research Institution | Chubu University |
Principal Investigator |
YAJIMA Ichiro Chubu University, 生命健康科学研究所, 研究員 (80469022)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 色素細胞学 / 循環器学 / 発生学 / 腫瘍学 / 色素細胞 / メラノサイト / 動脈管開存症 / メラニン |
Research Abstract |
Tyr : : Cre ; ss-catFloxedEx3 mice were generated by crossing Tyr : : Cre transgenic mice with ss-catFloxedEx3 mice. These mice showed PDA by enhanced activity of ss-catenin after birth. In these mice, ectopic melanocytes were localized in the heart and they directly and/or indirectly affect formation of the PDA.
|
Report
(3 results)
Research Products
(15 results)