regulation of hyaluronan production by keratinocytes
| Project/Area Number |
20790783
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|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
|---|
| Research Field |
Dermatology
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
OHTANI Tomoyuki Tohoku University, 病院, 助教 (20400319)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | ヒアルロン酸 / HABP / spongisis / spongiosis / 培養ヒト角化細胞 / HAS3 |
|---|
| Research Abstract |
The staining of HABP was enhanced in spongiosis. IL-4, IL-13, and IFN-・increased the hyaluronan production and enhanced the HAS3 mRNA expression by NHEK. Hyaluronan accumulation in the spongiotic epidermis was surrounded by keratinocytes.
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Report
(3 results)
Research Products
(5 results)
