• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Prostaglandin E(2)-EP3 signaling suppress skin inflammation in mouse contact hypersensitivity.

Research Project

Project/Area Number 20790798
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Dermatology
Research InstitutionKyoto University

Principal Investigator

HONDA Tetsuya  Kyoto University, 医学研究科, 助教 (40452338)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
KeywordsプロスタグランジンE2 EP3受容体 / 接触皮膚炎 / アレルギー・喘息 / 免疫 / プロスタグランジン
Research Abstract

Prostaglandin E2 is a lipid mediator, and EP3 is one of the receptor of PGE2. Administration of a EP3 selective agonist significantly suppressed mouse contact hypersensitivity response. EP3 signaling inhibited chemokine production from keratinocytes and suppressed inflammatory cell infiltration in contact hypersensitivity.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (3 results)

All 2009 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results)

  • [Journal Article] Prostaglandin E(2)-EP3 signaling suppress skin inflammation in mouse contact hypersensitivity.2009

    • Author(s)
      Tetsuya Honda, Toshiyuki Matsuoka, Mayumi Ueta, Kenji Kabashima, Yoshiki Miyachi, Shuh Narumiya
    • Journal Title

      Journal of Allergy and Clinical Immunology 124

      Pages: 809-818

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prostaglandin E(2)-EP3 signaling suppress skin inflammation in mouse contact hypersensitivity.2009

    • Author(s)
      本田哲也
    • Journal Title

      Journal of Allergy and Clinical Immunology 124

      Pages: 809-818

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] ProstaglandinE2-EP3 signaling suppress skin inflammation by inhibiting keratinocyte activation in mouse contact allergy2008

    • Author(s)
      本田哲也
    • Organizer
      International Investigative Dermatology 2008
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2008-05-17
    • Related Report
      2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi