A study for roles of platelets in the function and recruitment of dendritic cells

• Project/Area Number: 20790810
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Dermatology
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: MINEOKA Risa Kyoto Prefectural University of Medicine, 医学研究科, 助教 (80464585)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 血小板 / 樹状細胞 / 接触皮膚炎 / P-セレクチン

Research Abstract

Platelets play important roles in the recruitment of dendritic cells from blood to skin by forming platelet-dendritic cell complexes via P-selectin.

Research Products

• [Journal Article] Systemic allergic contact dermatitis due to phenylephrine in eyedrops, with a long-lasting allergic patch test reaction (2010)
  • Author(s): Risa Tamagawa-Mineoka
  • Journal Title: European Journal of Dermatology 20 Pages: 125-126
  • Peer Reviewed
• [Journal Article] Platelet-derived microparticles and soluble P-selectin as platelet activation markers in patients with atopic dermatitis (2009)
  • Author(s): Risa Tamagawa-Mineoka
  • Journal Title: Clinical Immunology 131 Pages: 495-500
  • Peer Reviewed
• [Journal Article] Platelets play important roles in the late phase of the immediate hypersensitivity reaction (2009)
  • Author(s): Risa Tamagawa-Mineoka
  • Journal Title: Journal of Allergy and Clinical Immunology 123 Pages: 581-587
  • Peer Reviewed
• [Journal Article] Elevated platelet activation in patients with atopic dermatitis and psoriasis : increased plasma levels of P-thromboglobulin and platelet factor 4 (2008)
  • Author(s): Risa Tamagawa-Mineoka
  • Journal Title: Allegology International 57 Pages: 391-396
  • Peer Reviewed
• [Presentation] 多数のステロイド外用剤の主剤で接触皮膚炎を生じた1例 (2009)
  • Author(s): 高橋三起子
  • Organizer: 第409回日本皮膚科学会京滋地方会
  • Place of Presentation: 滋賀県大津市
  • Year and Date: 2009-03-14
• [Presentation] 網状皮斑を主訴として壊死性血管炎の1例 (2009)
  • Author(s): 井上歩美
  • Organizer: 第409回日本皮膚科学会京滋地方会
  • Place of Presentation: 滋賀県大津市
  • Year and Date: 2009-03-14
• [Presentation] Platelets play important roles in recruitment of dendritic cells to skin in contact hypersensitivity. (2009)
  • Author(s): 峠岡理沙, 他
  • Organizer: The 34th Annual Meeting of the Japanese Society for Investigative Dermatology.
  • Place of Presentation: 福岡
• [Presentation] An important role for platelets in leukocyte recruitment to skin in allergic skin inflammation. (2009)
  • Author(s): 峠岡理沙, 他
  • Organizer: The 17th International Contact Dermatitis Symposium.
  • Place of Presentation: 京都
• [Presentation] 循環血中から皮膚組織への樹状細胞の供給における血小板の役割に関する研究 (2009)
  • Author(s): 峠岡理沙, 他
  • Organizer: 第19回日本樹状細胞研究会
  • Place of Presentation: 兵庫
• [Presentation] 皮膚の樹状細胞の機能と遊走における血小板の役割に関する研究 (2009)
  • Author(s): 峠岡理沙, 他
  • Organizer: 第108回日本皮膚科学会総会
  • Place of Presentation: 福岡
• [Presentation] 皮膚の樹状細胞の機能と遊走における血小板の役割に関する研究 (2009)
  • Author(s): 峠岡理沙
  • Organizer: 第108回日本皮膚科学会総会
  • Place of Presentation: 福岡国際会議場(福岡県)
• [Presentation] 循環血中から皮膚組織への樹状細胞の供給における血小板の役割に関する研究 (2009)
  • Author(s): 峠岡理沙
  • Organizer: 第19回日本樹状細胞研究会
  • Place of Presentation: 淡路夢舞台国際会議場(兵庫県)
• [Presentation] An important role for platelets in leukocyte recruitment to skin inallergic skin inflammation (2009)
  • Author(s): Risa Tamagawa-Mineoka
  • Organizer: The 17th International Contact Dermatitis Symposium
  • Place of Presentation: 京都国際会館(京都府)
• [Presentation] Platelets play important roles in recruitment of dendritic cells to skin in contact hypersensitivity (2009)
  • Author(s): Risa Tamagawa-Mineoka
  • Organizer: The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: JALリゾートシーホークホテル福岡(福岡県)
• [Presentation] The role of platelets in leukocyte recruitment in chronic contact hypersensitivity induced by repeated elicitation (2009)
  • Author(s): 峠岡理沙
  • Organizer: 第72回日本皮膚科学会東京支部学術大会
  • Place of Presentation: 東京都新宿区
• [Presentation] 血小板は皮膚の即時型アレルギー反応の遅発相において重要な役割を果たす (2008)
  • Author(s): 峠岡理沙
  • Organizer: 第34回免疫カンファレンス
  • Place of Presentation: 京都府京都市
  • Year and Date: 2008-10-25
• [Presentation] 筋症状として嚥下障害、構音障害のみを認めた皮膚筋炎の1例 (2008)
  • Author(s): 中井大介
  • Organizer: 第107回日本皮膚科学会総会
  • Place of Presentation: 京都府京都市
• [Presentation] Increased platelet activation markers in patients with atopic dermatitis (2008)
  • Author(s): Risa Tamagawa-Mineoka
  • Organizer: 5^<th> George Rajka International Symposium on Atopic Dermatitis
  • Place of Presentation: 京都府京都市
• [Presentation] Platelet P-selectin is required for leukocyte recruitment to skin in the late phase of immediate hypersensitivity reactions (2008)
  • Author(s): Risa Tamagawa-Mineoka
  • Organizer: International Investigative Dermatology 2008
  • Place of Presentation: 京都府京都市
• [Presentation] 成人アトピー性皮膚炎患者における血小板由来マイクロパーティクルの検討 (2008)
  • Author(s): 峠岡理沙
  • Organizer: 第20回日本アレルギー学会春季臨床大会
  • Place of Presentation: 東京都港区
• [Presentation] 乾癬患者における血漿中の血小板活性化マーカーの検討 (2008)
  • Author(s): 峠岡理沙
  • Organizer: 第23回日本乾癬学会学術大会
  • Place of Presentation: 北海道旭川市
• [Presentation] 塩酸フェニレフリンおよび塩化ベンザルコニウムによるアレルギー性接触皮膚炎の1例 (2008)
  • Author(s): 峠岡理沙
  • Organizer: 第38回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
  • Place of Presentation: 大阪府大阪市