Functional analysis of regulatory T cells in patient of drug hypersensitivity syndrome
| Project/Area Number |
20790815
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dermatology
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| Research Institution | Kyorin University |
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Principal Investigator |
TAKAHASHI Ryo Kyorin University, 医学部, 助教 (00317091)
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| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 皮膚炎症 / 再生学 / regulatory T cell / DIHS / SJS / ホーミング / 皮膚免疫 |
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| Research Abstract |
We investigated whether regulatory T cells (Treg cells) associated with the pathogenesis of severe drug eruptions. We have fined that the number of Treg cells and the expression of skin-homing receptors on Treg cells was significantly different between Drug-induced Hypersensitivity Syndrome (DIHS) and Stevens-Johnson Syndrome (SJS).
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Report
(3 results)
Research Products
(12 results)
