Effects of maternal separation stress on the newly generated cells

Research Project

Project/Area Number	20790834
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Psychiatric science
Research Institution	Shinshu University
Principal Investigator	FUKUSHIMA Nanae Shinshu University, 医学部, 助教 (90334888)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000) Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords	ストレス / 神経科学
Research Abstract	The numbers of newly generated cells in the hippocampal dentate gyrus, and the bulbar glomerular and granule cell layers were decreased by the repeated maternal separation during the suckling period. The decreases of newly generated cells were more pronounced in the maternally separated male rats than female rats, especially in the hippocampus. The effect of maternal separation stress on survival of the newly generated cells was gender-dependent.