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Correlation of cell surface antigens with individual differences in radiosensitivity in human hematopoietic stem/progenitor cells.

Research Project

Project/Area Number 20790874
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionHirosaki University

Principal Investigator

TAKAHASHI Kenji  Hirosaki University, 大学院・保健学研究科, 助教 (00400143)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords放射線 / 細胞・組織 / 再生医学シグナル伝達 / 生体分子 / 再生医学 / シグナル伝達
Research Abstract

To characterize the differences in the radiosensitivity of individual populations of human hematopoietic stem/progenitor cells, we examined the relationship among cell surface antigens, clonogenic potential and radiation survival.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (8 results)

All 2010 2009 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (2 results)

  • [Journal Article] Correlations of cell surface antigens with individual differences in radiosensitivity in human hematopoietic stem/progenitor cells.2010

    • Author(s)
      Takahashi K., Monzen S., Hayashi N., Kashiwakura I.
    • Journal Title

      Radiation Research 173

      Pages: 184-190

    • NAID

      130007000549

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Radiation sensitivities in the terminal stages of megakaryocytic maturation and platelet production.2010

    • Author(s)
      Monzen S., Takahashi K., Kashiwakura I. (6名中5番目)
    • Journal Title

      Radiation Research 172

      Pages: 314-320

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Correlations of cell surface antigens with individual differences in radio sensitivity in human hematopoietic stem/progenitor cells2010

    • Author(s)
      Takahashi K
    • Journal Title

      Radiation research 173

      Pages: 184-190

    • NAID

      130007000549

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of proteoglycan extracted from nasal cartilage of salmon heads on maturation of dendritic cells derived from human peripheral blood monocytes2010

    • Author(s)
      Yoshino H
    • Journal Title

      Biological and pharmaceutical bulletin 33

      Pages: 311-315

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Heavy ion beam irradiation regulates the mRNA expression in megakar yocytopoiesis from human hematopoietic stem/progenitor cells2009

    • Author(s)
      Monzen S
    • Journal Title

      Journal of radiation research 50

      Pages: 477-486

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between radiosensitivity and Nrf2 target gene expression in human hematopoietic stem cells.

    • Author(s)
      Kato K., Takahashi K., Kashiwakura I. (7名中2番目)
    • Journal Title

      Radiation Research (印刷中)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] ヒト造血幹細胞の放射線感受性における酸化ストレス応答機構の関与2009

    • Author(s)
      加藤健吾
    • Organizer
      日本放射線影響学会第52回大会
    • Place of Presentation
      広島
    • Related Report
      2009 Final Research Report
  • [Presentation] Effects of LET-radiation on human megakaryocytopoiesis and thrombopoiesis.2009

    • Author(s)
      Takahashi K.
    • Organizer
      ISEH 37th Annual Scientific Meeting
    • Place of Presentation
      Boston, USA
    • Related Report
      2009 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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