Development of a novel method for reducing renal accumulation of radiolabeled peptides
Project/Area Number |
20790882
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Radiation science
|
Research Institution | Health Sciences University of Hokkaido |
Principal Investigator |
AKIZAWA Hiromichi Health Sciences University of Hokkaido, 薬学部, 准教授 (90311795)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | がん / アイソトープ内用療法 / 体内動態制御 / 放射性医薬品 / 腎臓 / 刷子縁膜 / 酵素 / ペプチド |
Research Abstract |
When radiolabeled carcinophilic peptides are administered to cure cancer, renal accumulation of radioactivity, which causes side effect, is observed. My goal is the development of a novel strategy for reducing the renal radioactivity by the action of enzymes in kidneys. Useful information on the development was obtained from the present study.
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Report
(3 results)
Research Products
(1 results)