Development of a novel method for reducing renal accumulation of radiolabeled peptides

Research Project

Project/Area Number	20790882
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Radiation science
Research Institution	Health Sciences University of Hokkaido
Principal Investigator	AKIZAWA Hiromichi Health Sciences University of Hokkaido, 薬学部, 准教授 (90311795)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000) Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords	がん / アイソトープ内用療法 / 体内動態制御 / 放射性医薬品 / 腎臓 / 刷子縁膜 / 酵素 / ペプチド
Research Abstract	When radiolabeled carcinophilic peptides are administered to cure cancer, renal accumulation of radioactivity, which causes side effect, is observed. My goal is the development of a novel strategy for reducing the renal radioactivity by the action of enzymes in kidneys. Useful information on the development was obtained from the present study.

Report

(3 results)