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Target volume determination with four-dimensional CT in radiotherapy for lung cancer

Research Project

Project/Area Number 20790900
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionKumamoto University

Principal Investigator

SAITO Tetsuo  Kumamoto University, 医学部・附属病院, 医員 (30467980)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords肺癌 / 呼吸同期照射 / 4D-CT / 放射線治療
Research Abstract

At phase-based gating, the dosimetric parameters and treatment times are similar, irrespective of whether gating is around end-expiration or end-inspiration. At amplitude-based gating, a greater reduction in the lung dose is obtained when gating is around end-inspiration rather than end-expiration, however, the treatment time is prolonged considerably. When a 30% duty cycle is used, significant reduction in lung dose is achieved at the expense of modest prolongation of treatment time using phase-based gating around end-expiration.
Three dimensional tumor motion, craniocaudal tumor motion, and the craniocaudal tumor position are useful for predicting the benefit of respiratory-gated radiotherapy in lung cancer patients. Tumor volume is not a useful factor.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (4 results)

All 2009 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results)

  • [Journal Article] Comparison of gating around end-expiration and end-inspiration in radiotherapy for lung cancer2009

    • Author(s)
      Tetsuo Saito, Takashi Sakamoto, Natsuo Oya.
    • Journal Title

      Radiotherpy and Oncology 93

      Pages: 430-435

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of gating around end-expiration and end-inspiration in radiotherapy for lung cancer2009

    • Author(s)
      Tetsuo Saito
    • Journal Title

      Radiotherpy and Oncology 93

      Pages: 430-435

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 肺癌の呼吸同期照射における肺照射線量低下の大きさを予測する因子の検討2009

    • Author(s)
      斉藤哲雄
    • Organizer
      日本放射線腫瘍学会第22回学術大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-09-19
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 非小細胞肺癌に対するRPMシステムを用いた呼吸同期照射における同期範囲の検討2008

    • Author(s)
      斉藤哲雄
    • Organizer
      日本放射線腫瘍学会第21回学術大会
    • Place of Presentation
      札幌パークホテル
    • Year and Date
      2008-10-16
    • Related Report
      2009 Final Research Report 2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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