Target volume determination with four-dimensional CT in radiotherapy for lung cancer
| Project/Area Number |
20790900
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Kumamoto University |
|---|
Principal Investigator |
SAITO Tetsuo Kumamoto University, 医学部・附属病院, 医員 (30467980)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
|---|
| Keywords | 肺癌 / 呼吸同期照射 / 4D-CT / 放射線治療 |
|---|
| Research Abstract |
At phase-based gating, the dosimetric parameters and treatment times are similar, irrespective of whether gating is around end-expiration or end-inspiration. At amplitude-based gating, a greater reduction in the lung dose is obtained when gating is around end-inspiration rather than end-expiration, however, the treatment time is prolonged considerably. When a 30% duty cycle is used, significant reduction in lung dose is achieved at the expense of modest prolongation of treatment time using phase-based gating around end-expiration.
Three dimensional tumor motion, craniocaudal tumor motion, and the craniocaudal tumor position are useful for predicting the benefit of respiratory-gated radiotherapy in lung cancer patients. Tumor volume is not a useful factor.
|
Report
(3 results)
Research Products
(4 results)
