Fat-saturated diffusion-weighted imaging of the rat pelvis using three-dimensional water-excitation MP-RAGE MR sequence
Project/Area Number |
20790903
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Radiation science
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Research Institution | Tokyo Metropolitan University |
Principal Investigator |
NUMANO Tomokazu Tokyo Metropolitan University, 人間健康科学研究科, 助教 (10399511)
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Project Period (FY) |
2008 – 2009
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Project Status |
Completed (Fiscal Year 2009)
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Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Keywords | 核磁気共鳴画像(MRI) / 拡散強調画像(DWI) / Magnetic resonance imaging : MRI / Diffusion weighted imaging : DWI / Three-dimensional imaging / MP-RAGE法 / Tubo-FLASH法 / Three-dimensional DWI / CHESS法 / 水励起法 / Turbo-FLASH法 |
Research Abstract |
The purpose of this study was to develop a novel technique for fat-saturated three-dimensional (3D) diffusion-weighted (DW) MRI sequencing based upon the 3D magnetization-prepared rapid gradient-echo (3D-MP-RAGE) method. In order to saturate fat, two kinds of techniques were composed: the FatSat-3D-DWI sequence and WE-3D-DWI sequence, "chemical shift selective: CHESS (FatSat) method vs water excitation: WE method". The FatSat-3D-DWI sequence and WE-3D-DWI sequence were compared in terms of their degree of fat suppression. In the FatSat-3D-DWI sequence, the preparation phase with a "CHESS-90oRF-motion probing gradient : MPG-180oRF-MPG-90oRF" pulse-train was used to sensitize the magnetization to fat-saturated diffusion. In contrast, in the WE-3D-DWI sequence, a RAGE-excitation pulse with a "binominal-pulse 1-1 or 1-2-1" was selected for water-excited (fat-saturated) diffusion imaging. From experimental results obtained with a phantom, the effect of diffusion weighting and the effect of fat-saturation were confirmed. Fat saturation was much better in the WE-3D-DWI sequence than the CHESS-3D-DWI sequence. From animal (rat pelvis) experimental results using WE-3D-DWI, fat-saturated diffusion-weighted image data were obtained. This sequence was useful for in vivo imaging.
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Report
(3 results)
Research Products
(41 results)
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[Presentation] Simple method of magnetic resonance elastography2010
Author(s)
T. Numano1, 2), J. Hata1), Y. Takei3), T. Washio2), K. Mizuhara4), M. Niitsu1), K. Yagi1), E. Kobayashi3), K. Homma2)
Organizer
Austria EPOS of the European Congress of Radiology (ECR 2010)
Place of Presentation
Vienna, Austria
Related Report
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[Presentation] Development of a pneumatic vibrator evaluation device for MR Elastography2010
Author(s)
Y. Takei1), E. Kobayashi1), T. Numano2, 3), T. Washio3), K. Mizuhara4), M. Suga5), K. Homma3), C. Chui6), I. Sakuma1)
Organizer
Austria EPOS of the European Congress of Radiology (ECR 2010)
Place of Presentation
Vienna, Austria
Related Report
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[Presentation] Simple method of magnetic resonance elastography2010
Author(s)
I.Numano, J.Hata, Y.Takei, T.Washio, K.Mizuhara, M.Niitsu, K.Yagi, E.Kobayashi, K.Homma
Organizer
EPOS of the European Congress of Radiology (ECR 2010), C-3014
Place of Presentation
Vienna, Austria
Related Report
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[Presentation] Development of a Peneumatic vibrator evaluation device for MR Elastography2010
Author(s)
Y.Takei, E.Kobayshi, T.Numano, T.Washio, K.Mizuhara, M.Suga, K.Homma, C.Chui, I.Sakuma
Organizer
EPOS of the European Congress of Radiology (ECR 2010), C-2939
Place of Presentation
Vienna, Austria
Related Report
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[Presentation] 三次元MR Elastographyシーケンスの開発と性能評価2009
Author(s)
沼野智一1, 2), 鷲尾利克2), 武井祐介3), 水原和行4, 3), 小林英津子3), 島野俊4, 3), 新田尚隆2), 本間一弘2)
Organizer
第37回日本磁気共鳴医学会大会
Place of Presentation
横浜
Related Report
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[Presentation] Motion Sensitizing Gradientを用いない高速MREパルスシーケンスの臨床機への導入2009
Author(s)
沼野智一1, 3), 武井祐介2), 畑純一1), 鷲尾利克3), 水原和行4), 小林英津子2), 新津守1), 岩崎信明5), 八木一夫1), 本間一弘3)
Organizer
第37回日本磁気共鳴医学会大会
Place of Presentation
横浜
Related Report
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[Presentation] MR Elastographyのための加振装置の開発と評価2009
Author(s)
武井祐介1), 小林英津子1), 沼野智一2, 3), 鷲尾利克3), 水原和行4, 3), 島野俊4, 3), Chui Chee Kong5), 本間一弘3), 佐久間一郎2)
Organizer
第37回日本磁気共鳴医学会大会
Place of Presentation
横浜
Related Report
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[Presentation] RE画像におけるMSGの効能2009
Author(s)
鷲尾利克1), 水原和行2, 1), 沼野智一3, 1), 武井祐介4), 小林英津子4), 島野俊2, 1), 新田尚隆1), 本間一弘1)
Organizer
第37回日本磁気共鳴医学会大会
Place of Presentation
横浜
Related Report
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[Presentation] MREを行う簡便なシーケンスの提案とその評価2009
Author(s)
鷲尾利克1), 水原和行2, 1), 沼野智一3, 1), 畑純一3), 大島祐亮2, 1), 新田尚隆1), 工藤裕仁1), 八木一夫3), 本間一弘1)
Organizer
第58回理論応用力学講演会
Place of Presentation
東京
Related Report
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[Presentation] Motion Sensitizing Gradientを用いない高速MREパルスシーケンスの開発2008
Author(s)
沼野智一1, 2), 本間一弘2), 畑純一1, 2), 鷲尾利克2), 水原和行3, 2), 新田尚隆2), 大島裕亮3, 2), 工藤裕仁2), 八木一夫1)
Organizer
第36回日本磁気共鳴医学会大会
Place of Presentation
旭川
Related Report
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[Presentation] Motion Sensitizing Gradientを用いない高速MRE Pulse sequenceの応用2008
Author(s)
畑純一1, 2), 本間一弘2), 沼野智一1, 2), 鷲尾利克2), 水原和行3, 2), 新田尚隆2), 大島裕亮3, 2), 工藤裕仁2), 八木一夫1)
Organizer
第36回日本磁気共鳴医学会大会
Place of Presentation
旭川
Related Report
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