Development of prediction method for chemoradiation sensitivity by gene analysis -basic study with tumor cell line-

Research Project

Project/Area Number	20790908
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Radiation science
Research Institution	Keio University
Principal Investigator	FUKADA Junichi Keio University, 医学部, 助教 (50338159)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000) Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	放射線 / 生物学 / 遺伝子
Research Abstract	As result of this study, anti-sense method with fluorescence color by radiation exposure and the anticancer agent is a qualitative curative effect prediction by the gene expression, and an expecting application to the functional diagnostic imaging. On the other hand, I could not find the quantitative relationship between gene expression and radiation dose. Further examination is warranted to establish the prediction method for radiation sensitivity.