Hormonal effects on the appetite of patients after esophageal operation

• Project/Area Number: 20790952
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Digestive surgery
• Research Institution: Kyoto University
• Principal Investigator: MORI Yukiko Kyoto University, 医学研究科, 医員 (80456863)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 食道外科学 / 食指関連ホルモン / 食道癌 / 食思関連ホルモン / グレリン / ホルモン

Research Abstract

Patients who had gastroenterological resection often suffer from the appetite loss. Up to date, it has been thought that the appetite loss may be caused by the physical disorders. In this study, we show the imbalance of hormones related to appetite in the patients. Especially, it is important to find that ghrelin is in high level in the patients.

Research Products

• [Journal Article] large cystic gastrointestinal stromal tumor of the rectum in the retrorectal space. (2010)
  • Author(s): Takahashi R, Nagayama S, Mori Y, Isoda H, Yoshizawa A, Manabe T, Sakai Y
  • Journal Title: Int J Clin Oncol. (Epub ahead of print)
  • NAID: 10027665415
• [Journal Article] VEGF hypersecretion as a plausible mechanism for pseudo-meigs' syndrome in advanced colorectal cancer. (2010)
  • Author(s): Okuchi Y, Nagayama S, Mori Y, Kawamura J, Matsumoto S, Nishimura T, Yoshizawa A, Sakai Y
  • Journal Title: Jpn J Clin Oncol. 40(5) Pages: 476-481
• [Journal Article] A case report of pathologically complete response of a huge rectal cancer after systemic chemotherapy with mFOLFOX6. (2009)
  • Author(s): Okoshi K, Nagayama S, Furu M, Mori Y, Yoshizawa A, Toguchida J, Sakai Y
  • Journal Title: Jpn J Clin Oncol. 39(8) Pages: 528-533
• [Journal Article] A case report of pathologically complete response of a huge rectal cancer after systemic chemotherapy with mFOLFOX6. (2009)
  • Author(s): Okoshi K, et al.
  • Journal Title: Jpn J Clin Oncol. 39(8) Pages: 528-533
  • Peer Reviewed
• [Journal Article] Safety and efficacy of modified FOLFOX6 for treatment of metastatic or locally advanced colorectal cancer. A single-institution outcome study (2008)
  • Author(s): Matsumoto S, Nishimura T, Kanai M, Mori Y, Nagayama S, Kawamura J, Nomura A, Miyamoto S, Kitano T, Ishiguro H, Yanagihara K, Teramukai S, Sakai Y, Chiba T, Fukushima M
  • Journal Title: Chemotherapy 54(5) Pages: 395-403
• [Journal Article] Safety and efficacy of modified FOLFOX6 for treatment of metastatic or locally advanced colorectal cancer. A single-institution outcome (2008)
  • Author(s): Matsumoto S, Nishimura T, Kanai M, Mori Y, et.al.
  • Journal Title: Chemotherapy 54 Pages: 395-403
  • Peer Reviewed