| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
Brain tumor stem cell (BTSC) play a role of source cell to form and maintain the brain tumor mass. In this study, we successfully established the BTSC cell lines and showed the anti-tumor effect of neurotransmitters as apomorphine, PAPP, ifenprodil, indatraline, sertraline, tegaserod on BTSC. In addition, we showed the anti-tumor effect on BTSC using photodynamic therapy technique using 5-aminolevulinic acid. These results become the cornerstone for development of BTSC target therapy.
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