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Usefulness of diffusion MRI for assessment of the patients with treated brain tumor

Research Project

Project/Area Number 20791021
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Cerebral neurosurgery
Research InstitutionOsaka Medical College

Principal Investigator

YAMADA Yoshitaka  Osaka Medical College, 医学部, 非常勤講師 (00368101)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords拡散強調像 / MRI / 脳腫瘍 / ADC値 / 治療効果判定 / ホウ素中性子捕捉療法 / 治療評価
Research Abstract

Assessment of therapeutic efficiency for malignant glioma patient is traditionally accomplished by measuring changes in tumor size in gadolinium-enhanced T1-weighted MRI at 10 weeks after treatment has been administered. In this study, we evaluated glioblastoma (GB) patients treated by boron neutron capture therapy (BNCT) by using this fDM analysis. The maximum volume of tumor with decrease diffusion by fDM within 7 days was the strongest predictor of patients' survival time since BNCT. The fDM could provide an earlier imaging assessment of the prognosis of GB patients treated by BNCT.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (19 results)

All 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (17 results)

  • [Journal Article] ^<18>F-BPA-PETを用いた悪性脳腫瘍治療後の病態解析2009

    • Author(s)
      川端信司・山田佳孝, ほか(10人中7番)
    • Journal Title

      CI研究 31巻

      Pages: 145-151

    • NAID

      10026325247

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] ^<18>F-BPA-PETを用いた悪性脳腫瘍治療後の病態解析2009

    • Author(s)
      川端信司、山田佳孝, ほか
    • Journal Title

      CI研究 31

      Pages: 145-151

    • NAID

      10026325247

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] functional Diffusion Mapを用いたホウ素中性子捕捉療法後の治療効果判定2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      第27回日本脳腫瘍学会
    • Place of Presentation
      りんくうゲートタワーホテル
    • Year and Date
      2009-11-09
    • Related Report
      2009 Final Research Report
  • [Presentation] functional Diffusion Map を用いたホウ素中性子捕捉療法後の治療効果判定2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      第27回日本脳腫瘍学会
    • Place of Presentation
      りんくう国際会議場(大阪)
    • Year and Date
      2009-11-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] New imaging assessment: functional Diffuison Map for brain tumors patients treated by Boron Neutron Capture Therapy2009

    • Author(s)
      Ryo Hiramatsu, Yoshitaka Yamada, et al
    • Organizer
      2009 Joint of the Society for Neuro-Oncology and the AANS/CNS Section on Tumors
    • Place of Presentation
      the Hilton New Orleans Riverside
    • Year and Date
      2009-10-23
    • Related Report
      2009 Final Research Report
  • [Presentation] New imaging assessment : functional Diffuison Map for brain tumors patients treated by Boron Neutron Capture Therapy2009

    • Author(s)
      Hiramatsu, Yamada, ほか
    • Organizer
      2009 Joint of the Society for Neuro-Oncology and the AANS/CNS Section on Tumors
    • Place of Presentation
      the Hilton New Orleans Riverside
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] functional Diffusion Mapを用いた早期治療効果判定:ホウ素中性子捕捉療法により治療した悪性神経膠腫19症例を対象2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      日本脳神経外科学会 第68回学術総会
    • Place of Presentation
      京王プラザホテル
    • Year and Date
      2009-10-15
    • Related Report
      2009 Final Research Report
  • [Presentation] functional Diffusion Map を用いた早期治療効果判定:ホウ素中性子捕捉療法により治療した悪性神経膠腫19症例を対象2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      日本脳神経外科学会 第68回学術総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2009-10-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] New imaging assessment: functional Diffuison Map for brain tumors patients treated by boron neutron capture therapy2009

    • Author(s)
      Ryo Hiramatsu, Yoshitaka Yamada, et al
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-03
    • Related Report
      2009 Final Research Report
  • [Presentation] New imaging assessment : functional Diffuison Map for brain tumors patients treated by boron neutron capture therapy2009

    • Author(s)
      Hiramatsu, Yamada, ほか
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2009-10-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] MRIの経時的ADC値解析画像によるホウ素中性子捕捉療法後の治療効果判定2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      日本放射線腫瘍学会第22回学術大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-09-17
    • Related Report
      2009 Final Research Report
  • [Presentation] MRIの経時的ADC値解析画像によるホウ素中性子捕捉療法後の治療効果判定2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      日本放射線腫瘍学会 第22回学術大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] functional Diffuion Mapを用いたホウ素中性子捕捉療法(BNCT)後の画像解析と効果判定2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      第12回日本病院脳神経外科学会
    • Place of Presentation
      ホテルニューオータニ大阪
    • Year and Date
      2009-07-18
    • Related Report
      2009 Final Research Report
  • [Presentation] functional Diffuion Map を用いたホウ素中性子捕捉療法(BNCT)後の画像解析と効果判定2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      第12回日本病院脳神経外科学会
    • Place of Presentation
      ホテルニューオータニ大阪(大阪)
    • Year and Date
      2009-07-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] ADC値増減評価を用いた硼素中性子捕捉療法後malignant gliomaの画像評価2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      第69回近畿脳腫瘍研究会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2009-04-04
    • Related Report
      2009 Final Research Report
  • [Presentation] ADC値増減評価を用いた棚素中性子捕捉療法後malignant gliomaの画像評価2009

    • Author(s)
      山田佳孝、平松亮、池田直廉, ほか
    • Organizer
      第69回近畿脳腫瘍研究会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2009-04-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 再発悪性神経膠腫と放射線壊死の鑑別:拡散テンソルイメージ(DTI)の有用性2009

    • Author(s)
      池田直廉・山田佳孝, ほか
    • Organizer
      第32回日本脳神経CI学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-03-07
    • Related Report
      2009 Final Research Report
  • [Presentation] ホウ素中性子捕捉療法(Boron neutron capture therapy)による悪性神経膠腫治療の画像評価2009

    • Author(s)
      平松亮・山田佳孝, ほか
    • Organizer
      第32回日本脳神経CI学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-03-07
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 再発悪性神経膠腫と放射線壊死の鑑別 : 拡散テンソルイメージ(DTI)の有用性2009

    • Author(s)
      山田佳孝、平松亮、池田直廉, ほか
    • Organizer
      第32回日本脳神経CI学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-03-07
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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