Isolation and characterization of a novel peptide from gastrointenstinal tract associated with osteoblast differentiation and bone formation
Project/Area Number |
20791058
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Orthopaedic surgery
|
Research Institution | Kurume University |
Principal Investigator |
FUKUSHIMA Nobuhiro Kurume University, 医学部, 助教 (90412535)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | ペプチド / 骨芽細胞 / 分化 / 骨密度 / 消化管 / カルシウム |
Research Abstract |
We discovered a novel peptide which is a positive regulator that acts directly on osteoblasts. This peptide directly promotes osteoblast differentiation in vitro and increases bone mineral density in vivo. The discovery of novel peptide may provide a new treatment option for osteoporosis and fracture healing.
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Report
(3 results)
Research Products
(2 results)