The effect of polytangstate at LGIC receptor.

• Project/Area Number: 20791071
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Anesthesiology/Resuscitation studies
• Research Institution: Osaka University
• Principal Investigator: UETA Kazuyoshi Osaka University, 医学系研究科, 助教 (90432533)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: MRSA / VRSA / タングステン酸 / LGIC受容体 / けいれん / NPPV / ヘルメット / 加温 / NMDA受容体 / ポリタングステン酸 / GABA受容体 / プラバスタチン / アモキサピン

Research Abstract

Convulsion is likely to be associated with antagonism of GABA receptor by polytangstate and with potentiation of NMDA receptor by high concentration of tungsten oxide in vitro. For patient comfort during CPAP using a helmet, the most desirable conditions are likely to obtained by humidifying without heating, that is by leaving the water in the humidifier chamber at room temperature.

Research Products

• [Journal Article] Eisenmenger症候群を合併した心室中隔欠損症に対する心肺同時移植術後集中治療管理の経験。 (2010)
  • Author(s): 植田一吉・高山千尋・後藤幸子・平尾収・大田典之・内山昭則・眞下節・藤野裕士
  • Journal Title: 日本集中治療医学会雑誌 17(4) Pages: 539-540
  • NAID: 10027854363
  • Peer Reviewed
• [Journal Article] Eisenmenger症候群を合併した心室中隔欠損症に対する心肺同時移植術後集中治療管理の経験 (2010)
  • Author(s): 植田一吉・内山昭則・眞下節・藤野裕士, ほか3名
  • Journal Title: 日本集中治療医学会雑誌 Volume: 17(4) Pages: 539-540
  • NAID: 10027854363
  • Peer Reviewed
• [Presentation] Humidification and temperature when a using helmet for noninvasive positive pressure ventilation (2010)
  • Author(s): Kazuyoshi Ueta, Toshiji Tomita, Akinori Uchiyama, Noriyuki Ohta, Naoya Iguchi, Yukiko Goto, Takashi Mashimo, Yuji Fujino
  • Organizer: ESICM
  • Place of Presentation: Barcelona
  • Year and Date: 2010-10-19
• [Presentation] ヘルメットを用いた非侵襲陽圧換気(NPPV)において加温必要性の検討 (2010)
  • Author(s): 植田一吉 井口直也 小山有紀子 冨田敏司 後藤幸子 高山千尋 平尾収 大田典之 内山昭則 眞下節 藤野裕士
  • Organizer: 第37回日本集中治療医学会
  • Place of Presentation: 広島
  • Year and Date: 2010-03-04
• [Presentation] Humidification and temperature when a using helmet for noninvasive positive pressure ventilation (2010)
  • Author(s): Kazuyoshi Ueta, ほか7名
  • Organizer: European Society of Intensive Care Medicine
  • Place of Presentation: Barcelona, Spain
• [Presentation] Eisenmenger症候群を合併した心室中隔欠損症に対し心肺同時移植を行った一例 (2009)
  • Author(s): 植田一吉
  • Organizer: 第54回日本集中治療医学会近畿地方会
  • Place of Presentation: 和歌山
  • Year and Date: 2009-06-27
• [Presentation] 急激な低血糖のため管理に難渋した新生児奇形腫摘出術の術後管理 (2009)
  • Author(s): 植田一吉
  • Organizer: 第36回日本集中治療医学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-02-27