Pathosis and control of splanchnic circulation in septic shock
| Project/Area Number |
20791080
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Anesthesiology/Resuscitation studies
|
|---|
| Research Institution | Nagasaki University |
|---|
Principal Investigator |
SEKINO Motohiro Nagasaki University, 病院, 助教 (40380927)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
|---|
| Keywords | 敗血症性ショック / 腸管循環カ / ルペリチド / 腸管循環 / カルペリチド |
|---|
| Research Abstract |
In porcine fluid-resuscitated endotoxemia model, a low dose of carperitide, a synthetic atrial natriuretic peptide, administered prior to endotoxemia maintained systemic and splanchnic circulation, and prevented the deterioration of oxygenation. Carperitide infusion is a potentially beneficial therapy with respect to systemic and splanchnic circulation as well as the respiratory system during sepsis.
|
Report
(4 results)
Research Products
(19 results)
