Clinical analysis of analgesic effect and mechanism of transdermal amitriptyline on refractory pain

Research Project

Project/Area Number	20791081
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Anesthesiology/Resuscitation studies
Research Institution	Nagasaki University
Principal Investigator	SAKAI Tetsuya Nagasaki University, 大学院・医歯薬学総合研究科, 助教 (70346948)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords	抗うつ薬 / 経皮投与 / 難治性疼痛 / 電流知覚閾値 / 神経遮断効果 / アミトリプチリン
Research Abstract	When amitriptyline is applied transdermally, quantitative and selective evaluation of sensory nerve shows that the blocking effect is exerted in all types of sensory fibers and lasts for four hours.

Report

(3 results)